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Symbol Name ID |
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit MGI:107940 |
| Darker colors indicate more annotations |
| Human Phenotypes | Spasticity |
Delayed CNS myelination |
Lateral ventricle dilatation |
Ventriculomegaly |
Absent septum pellucidum |
Cerebellar hypoplasia |
Poor fine motor coordination |
Slurred speech |
Abnormally low-pitched voice |
Delayed speech and language development |
Dysarthria |
Atypical behavior |
Polyphagia |
Intellectual disability |
Intellectual disability, mild |
Postural instability |
Global developmental delay |
Seizure |
Bilateral tonic-clonic seizure |
Generalized non-motor (absence) seizure |
| Disease(s) Associated with EZH2 | ||||||||||||||||||||
| Weaver syndrome |
| Mouse Phenotypes | abnormal neuron differentiation |
abnormal oligodendrocyte morphology |
dysmyelination |
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| Availability | Mouse Genotype | |||
| Ezh2tm1Yugo/Ezh2tm1Yugo Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ (conditional) |
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| Ezh2tm1Yugo/Ezh2tm1Yugo Tg(Nes-cre/ERT2)5-1Imayo/0 (conditional) |
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| Ezh2tm2Sho/Ezh2tm2Sho Olig1tm1(cre)Rth/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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